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  • Title: Cytotoxic activity of lignans from Hibiscus cannabinus.
    Author: Moujir L, Seca AM, Silva AM, López MR, Padilla N, Cavaleiro JA, Neto CP.
    Journal: Fitoterapia; 2007 Jul; 78(5):385-7. PubMed ID: 17512680.
    Abstract:
    The antimicrobial and cytotoxic activities of six lignans isolated from the core and bark acetone extracts of Hibiscus cannabinus have been investigated. Two compounds (2 and 3) showed strong cytotoxic activity against HeLa, Hep-2 and A-549 cell lines while compound 5 showed moderate activity on HeLa cells when they were in advanced stage of cellular division. The compounds did not exhibit antimicrobial activity.
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