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  • Title: Effect of epsilon-aminocaproylamino acids on fibrin formation.
    Author: Bruzgo I, Midura-Nowaczek K, Bruzgo M, Kaczyńska J, Roszkowska-Jakimiec W.
    Journal: Acta Pol Pharm; 2006; 63(2):149-52. PubMed ID: 17514879.
    Abstract:
    Effect of three epsilon-aminocaproylamino acids with significant antifibrinolytic activity on polymerization of fibrin monomer, clot retraction, fibrin structure, prothrombin consumption and thrombin activity was examined. epsilon-Aminocaproyl-L-norleucine and epsilon-aminocaproyl-L-leucine were weak inhibitors of thrombin activity and epsilon-aminocaproyl-L-norleucine slightly inhibited polymerization of fibrin monomers.
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