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  • Title: Pregnancies complicated by multidrug-resistant tuberculosis and HIV co-infection in Durban, South Africa.
    Author: Khan M, Pillay T, Moodley J, Ramjee A, Padayatchi N.
    Journal: Int J Tuberc Lung Dis; 2007 Jun; 11(6):706-8. PubMed ID: 17519106.
    Abstract:
    SETTING: Tertiary hospitals in KwaZulu Natal, South Africa. OBJECTIVE: To study the impact of multidrug-resistant tuberculosis (MDR-TB) and human immunodeficiency virus-1 (HIV-1) co-infection during pregnancy on maternal and perinatal outcome. DESIGN: Prospective study performed between 1996 and 2001. Symptomatic pregnant women were investigated for TB. Those with confirmed MDR-TB were reported on. RESULTS: Three of five pregnant women with MDR-TB were HIV-1 co-infected. One woman decided to terminate the pregnancy and one experienced pre-term labour. Two neonates had features of growth restriction. CONCLUSION: Management of pregnant women with MDR-TB in an HIV-endemic area is possible in developing countries.
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