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  • Title: Intraoperative monitoring of hearing during cerebellopontine angle tumor surgery using transtympanic electrocochleography.
    Author: Morawski KF, Niemczyk K, Bohorquez J, Marchel A, Delgado RE, Ozdamar O, Telischi FF.
    Journal: Otol Neurotol; 2007 Jun; 28(4):541-5. PubMed ID: 17529854.
    Abstract:
    OBJECTIVE: To investigate the use of transtympanic electrocochleography (TT-ECochG) analyzed on-line by a detector strategy software that made possible automatic extraction of TT-ECochG components intraoperatively in real-time domain. PATIENTS: Fifteen patients with cerebellopontine angle tumor among 50 patients were included in this study. INTERVENTION: All subjects were operated on via middle fossa or retrosigmoid approach. Pure-tone average (PTA) was measured at 0.5, 1.0, and 2.0 kHz, and calculations were performed before and after surgery. Auditory function was monitored intraoperatively via TT-ECochG, and analyzed data were displayed on-line. MAIN OUTCOME MEASURES: TT-ECochG changes in morphology were described. Postoperative PTA elevation level correlated with TT-ECochG morphology changes occurring intraoperatively. RESULTS: Analyzed on-line, TT-ECochG data were displayed as first negative peak of compound action potential amplitude and latency in time domain every 3 to 5 seconds. A good correlation between postoperative PTA elevation and TT-ECochG morphology changes was showed (Spearman rank test, R = +0.93; t(N-2) = 9.00; p < 0.0001). CONCLUSION: TT-EcochG seemed to effectively mirror even minimal changes in auditory function during intraoperative monitoring in real-time domain. Developed strategy of on-line analysis makes the intraoperative hearing status assessment faster and easier.
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