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  • Title: Musk-antibody positive myasthenia gravis presenting with isolated neck extensor weakness.
    Author: Casasnovas C, Povedano M, Jaumà S, Montero J, Martínez-Matos JA.
    Journal: Neuromuscul Disord; 2007 Jul; 17(7):544-6. PubMed ID: 17533129.
    Abstract:
    Dropped head sign is characterized by the gradual forward sagging of the head due to weakness of neck extensor muscles. This may be a prominent sign of several neuromuscular disorders and may be an isolated feature of myasthenia gravis (MG). We describe a patient with isolated neck extensor weakness, eletrophysiological findings suggesting myasthenia gravis and positive MuSK antibodies. This case supports that finding anti-MuSK antibodies may be extremely helpful in dropped head patients and negative acetylcholine receptor antibodies especially if needle EMG does not reveal myopathic or neurogenic patterns.
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