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  • Title: [Re-osseointegration of peri-implantitis bone defects: an experimental study in dogs].
    Author: Zou DR, Zhu H, Qu XH.
    Journal: Shanghai Kou Qiang Yi Xue; 2006 Dec; 15(6):614-8. PubMed ID: 17533714.
    Abstract:
    PURPOSE: To investigate the treatment methods of experimentally induced peri-implantitis bone defects, and evaluate bone regeneration and re-osseointegration around implants histologically. METHODS: 30 Brinemark standard implants were placed in 5 Beagle dogs' mandibles to establish peri-implantitis bone defect model, then bone defects were randomly treated with: (1) debridement alone; (2) debridement plus guided bone regeneration using non-absorbable membrane; (3) debridement plus non-absorbable membrane associated with bone graft; (4) debridement plus non-absorbable membrane associated with biological activity glass. Peri-implant bone augmentation was observed and detected by radiography, fluorescence light micrography, un-decalcified bones ground section and direct measurement on operation. SPSS 12.0 software package was used for ANOVA, Kruskal-Wallis test and Mann-Whiteney test. RESULTS: There were significant differences between four groups in peri-implant bone augmentation, bone contact level and bone mineralization apposition rate, P < 0.05. The group using debridement plus non-absorbable membrane associated with bone graft resulted in a greater amount of regeneration than the other treatments. CONCLUSION: Inflammation induced peri-implant bone defects can regenerate by appropriate treatment. Supported by Shanghai Municipal Science and Technology Enhancement Award (Grant No.024119072).
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