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  • Title: Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome.
    Author: Soares EM, Azevedo GD, Gadelha RG, Lemos TM, Maranhão TM.
    Journal: Fertil Steril; 2008 Mar; 89(3):649-55. PubMed ID: 17543961.
    Abstract:
    OBJECTIVE: To determine the prevalence of the metabolic syndrome (MetS) and its components in Brazilian women with polycystic ovary syndrome (PCOS). DESIGN: Cross-sectional study. SETTING: University Hospital, Federal University of Rio Grande do Norte, Natal-RN, Brazil. PATIENT(S): 102 women with PCOS by the Rotterdam consensus criteria. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Clinical and biochemical parameters for MetS as defined by the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III). RESULT(S): The prevalence for individual components of MetS were high-density lipoprotein cholesterol level <50 mg/dL in 69.6%, waist circumference >or=88 cm in 57.9%, triglyceride level >or=150 mg/dL in 31.7%, blood pressure >or=130/85 mm Hg in 18.6%, and fasting glucose concentrations >or=110 mg/dL in 2.9%. Three or more of these individual criteria were present in 29 (28.4%) of the patients. The prevalence of MetS increased with body mass index: 3.2%, 19.2% and 52.3% for normal, overweight, and obese women, respectively. CONCLUSION(S): These findings indicate that Brazilian women with PCOS have a high prevalence of MetS and its individual components, particularly a decreased high-density lipoprotein cholesterol level. Thus, these women are at increased risk of diabetes mellitus and cardiovascular disease.
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