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  • Title: [Application of electrostatic spinning technology in nano-structured polymer scaffold].
    Author: Chen D, Li M, Fang Q.
    Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2007 Apr; 21(4):411-5. PubMed ID: 17546890.
    Abstract:
    OBJECTIVE: To review the latest development in the research on the application of the electrostatic spinning technology in preparation of the nanometer high polymer scaffold. METHODS: The related articles published at home and abroad during the recent years were extensively reviewed and comprehensively analyzed. RESULTS: Micro/nano-structure and space topology on the surfaces of the scaffold materials, especially the weaving structure, were considered to have an important effect on the cell adhesion, proliferation, directional growth, and biological activation. The electrospun scaffold was reported to have a resemblance to the structure of the extracellular matrix and could be used as a promising scaffold for the tissue engineering application. The electrospun scaffolds were applied to the cartilage, bone, blood vessel, heart, and nerve tissue engineering fields. CONCLUSION: The nano-structured polymer scaffold can support the cell adhesion, proliferation, location, and differentiation, and this kind of scaffold has a considerable value in the tissue engineering field.
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