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  • Title: [Application of autologous platelet-rich gel to refractory chronic diabetic cutaneous ulcers].
    Author: Yuan N, Ran X.
    Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2007 Apr; 21(4):426-9. PubMed ID: 17546893.
    Abstract:
    OBJECTIVE: To review and evaluate the clinical application of autologous platelet-rich gel (APG) in refractory chronic diabetic cutaneous ulcers. METHODS: The latest literature was extensively reviewed, and the potential mechanism of APG for healing diabetic cutaneous ulcers was discussed. RESULTS: APG accelerated the ulcer healing, especially in healing the refractory diabetic cutaneous ulcers, and the high-level growth factors from the platelet releasate were thought to be the major potential mechanism of the APG action. CONCLUSION: APG can promote the healing of refractory chronic diabetic cutaneous ulcers. Topical haemotherapy with APG may be considered an adjuvant treatment of a multidisciplinary process and may be useful to the effective therapy of cutaneous ulcers.
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