These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Efficacy of chloroquine and sulfadoxine/pyrimethamine mono- and combined therapy against falciparum malaria in Sudan.
    Author: Elamin SB, Malik el-FM, Ahmed el-DS, Elabadil EK, Mohamad TA.
    Journal: East Mediterr Health J; 2007; 13(1):25-34. PubMed ID: 17546902.
    Abstract:
    We assessed the efficacy of chloroquine and sulfadoxine/pyrimethamine monotherapy in several sentinel sites in northern Sudan and the efficacy of combined therapy in 2 sites. Chloroquine efficacy in children under 5 years was also assessed in 2 sites in southern Sudan. Patients with indications of uncomplicated falciparum malaria and sufficient parasite density were enrolled. The chloroquine failure rates in the northern and southern sites were 43.4% and 80.2% respectively. Treatment failure was significantly higher in children than adults, while there was no significant sex difference. Sulfadoxine/pyrimethamine had an overall failure rate of 4.4%. Combination of the 2 drugs had a failure rate of 14.5% and 5.9% in the 2 sites.
    [Abstract] [Full Text] [Related] [New Search]