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  • Title: Mutagenicity studies of kojic acid.
    Author: Wei CI, Huang TS, Fernando SY, Chung KT.
    Journal: Toxicol Lett; 1991 Dec; 59(1-3):213-20. PubMed ID: 1755028.
    Abstract:
    Kojic acid, a fungal metabolite produced by some species of Aspergillus and Penicillium, was found to induce sister chromatid exchanges and chromosomal aberrations in Chinese hamster ovary cells in the presence or absence of the rat liver S9 mix. Furthermore, this compound was demonstrated to induce mutations in Salmonella typhimurium strains TA98 and TA100 using both plate-incorporation and preincubation methods.
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