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  • Title: [Ultramorphometry of cells in a hamster embryo fibroblast culture following transformation by Rous sarcoma virus].
    Author: Iagubov AS, Ageenko AI, Chutkov NA.
    Journal: Vopr Onkol; 1975; 21(7):62-6. PubMed ID: 175575.
    Abstract:
    Changes in mitochondria, ergastoplasma and the polyribosomal apparatus of FHE (fibroblasts of hamster embryo) cell culture were studied in the kinetics of their malignification with Rous sarcoma virus. Considerable alterations were revealed in the organization of protein-synthetising cytoplasmic organells, manifested in the pronounced enhancement of nonspecific protein synthesis and reduction of ergastoplasma. This process starts immediately after the infection and shows a character approximating the exponents. On the part of the mitochondrial apparatus no differences between the experiment and control were revealed.
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