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  • Title: Cognitive deficits during status epilepticus and time course of recovery: a case report.
    Author: Van Paesschen W, Porke K, Fannes K, Vandenberghe R, Palmini A, Van Laere K, Dupont P.
    Journal: Epilepsia; 2007 Oct; 48(10):1979-83. PubMed ID: 17561953.
    Abstract:
    We describe a young woman with progressive cognitive and neurological deficits during a parietal lobe status epilepticus (SE). Ictal FDG-PET showed left parietal lobe hypermetabolism and frontal lobe hypometabolism with concomitant EEG slowing. Cognitive and neurological deficits fully reversed more than 1 year after seizure remission, and were associated with normalization of FDG-PET and EEG. Our findings suggest that ictal hypometabolism and EEG delta activity at a distance from the epileptic focus were seizure-related phenomena, possibly representing inhibition in seizure propagation pathways, which could be responsible for the epileptic encephalopathy.
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