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  • Title: Partial trisomy 1q. A nonrandom primary chromosomal abnormality in myelodysplastic syndromes?
    Author: Fonatsch C, Haase D, Freund M, Bartels H, Tesch H.
    Journal: Cancer Genet Cytogenet; 1991 Oct 15; 56(2):243-53. PubMed ID: 1756470.
    Abstract:
    Cytogenetic and clinical data of 11 patients with de novo myelodysplastic syndromes and partial or total trisomy of the long arm of chromosome 1 are presented. In eight of these patients trisomy 1q was the sole karyotypic change and therefore can be classified as a primary chromosome anomaly. A remarkably young median age of 36.5 years was noticed in this patient group.
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