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  • Title: Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines.
    Author: Dang Z, Yang Y, Ji R, Zhang S.
    Journal: Bioorg Med Chem Lett; 2007 Aug 15; 17(16):4523-6. PubMed ID: 17566733.
    Abstract:
    The design and synthesis of new fluoroquinolone antibacterial agents having substituted piperidine rings at the C-7 position are described. Most of the new compounds demonstrated high in vitro antibacterial activity. Several of them exhibited significant activities against gram-positive organisms, which were more potent than those of gemifloxacin, Linezolid, and vancomycin.
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