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  • Title: [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor.
    Author: Smith CD, Baxendale IR, Lanners S, Hayward JJ, Smith SC, Ley SV.
    Journal: Org Biomol Chem; 2007 May 21; 5(10):1559-61. PubMed ID: 17571184.
    Abstract:
    The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.
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