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Title: Gastrointestinal stromal tumors involving the prostate: presentation, course, and therapeutic approach. Author: Arce-Lara C, Shah MH, Jimenez RE, Patel VR, Benson DM, Clinton SK, Monk JP. Journal: Urology; 2007 Jun; 69(6):1209.e5-7. PubMed ID: 17572224. Abstract: Gastrointestinal stromal tumors are relatively rare soft-tissue neoplasms arising from the gastrointestinal tract. The clinical presentation of gastrointestinal stromal tumors varies and depends on the tumor size and location. We present 2 patients with a gastrointestinal stromal tumor who presented with genitourinary symptoms and were diagnosed by transrectal ultrasound-guided prostate biopsy. We describe the clinical presentation and diagnostic and therapeutic approach to these cases, highlighting the successful preoperative use of imatinib mesylate (Gleevec) followed by prostatectomy.[Abstract] [Full Text] [Related] [New Search]