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  • Title: Gastrointestinal stromal tumors involving the prostate: presentation, course, and therapeutic approach.
    Author: Arce-Lara C, Shah MH, Jimenez RE, Patel VR, Benson DM, Clinton SK, Monk JP.
    Journal: Urology; 2007 Jun; 69(6):1209.e5-7. PubMed ID: 17572224.
    Abstract:
    Gastrointestinal stromal tumors are relatively rare soft-tissue neoplasms arising from the gastrointestinal tract. The clinical presentation of gastrointestinal stromal tumors varies and depends on the tumor size and location. We present 2 patients with a gastrointestinal stromal tumor who presented with genitourinary symptoms and were diagnosed by transrectal ultrasound-guided prostate biopsy. We describe the clinical presentation and diagnostic and therapeutic approach to these cases, highlighting the successful preoperative use of imatinib mesylate (Gleevec) followed by prostatectomy.
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