These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Study on enantioselectivity of celluloses derived by phenylcarbamate at 2,3- or 2,3,6-positions].
    Author: Chang Y, Zhou L, Yuan L.
    Journal: Se Pu; 2007 Mar; 25(2):203-6. PubMed ID: 17580686.
    Abstract:
    Cellulose-2, 3, 6-trisphenylcarbamate, cellulose-2, 3-bisphenylcarbamate, cellulose2,3,6-tris(3,5-dimethylphenylcarbamate) and cellulose-2,3-bis(3,5-dimethylphenylcarbamate) were synthesized and respectively coated on silica gel as chiral stationary phases for high performance liquid chromatography (HPLC). Nine pairs of enantiomers, which are ( +/- )-phenyl-1, 2-ethanediol, ( +/- )-2-phenyl-1 -propanol, DL-alpha-methylbenzylamine, DL-mandelic acid, ( +/- ) -1-(1-naphthyl) ethanol, ( +/- ) -propranolol, ( +/- ) -3-benzyloxy-1, 2-propanediol, DL-tyrosine and ( +/- ) -di-O, O-p-toluyl-D-tartaric acid, were separated using hexane-isopropanol as mobile phase on the columns packed with the chiral stationary phases. For comparative reasons, the ratio of hexane/isopropanol in the eluent was kept at 9: 1 (v/v) in all experiments, and the chromatographic separations were performed at 30 degrees C with a flow rate of 0. 5 mL/min. All the test solutes were detected at 254 nm. The results showed that enantioseparation of cellulose-2,37bisphenylcarbamate was better than cellulose-2,3,6-trisphenylcarbamate for the test enantiomers, and cellulose-2,3-bis (3 ,5-dimethylphenylcarbamate) had low retention factors and short analysis times for most enantiomers and good separation factors for some racemates compared to cellulose-2,3,6-tris(3,5-dimethylphenylcarbamate).
    [Abstract] [Full Text] [Related] [New Search]