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  • Title: Synthesis of hyaluronic acid oligomers using Ph2SO/Tf2O-mediated glycosylations.
    Author: Dinkelaar J, Codée JD, van den Bos LJ, Overkleeft HS, van der Marel GA.
    Journal: J Org Chem; 2007 Jul 20; 72(15):5737-42. PubMed ID: 17585821.
    Abstract:
    The synthesis of hyaluronic acid (HA) oligomers using a stepwise glycosylation strategy is described. This method employs protected 1-hydroxyuronic acid and 1-phenylthio glucosamine donors, both of which are activated with the Ph2SO/Tf2O activator system.
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