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  • Title: [The pathogenetic and prognostic significance of the level of class-E immunoglobulins in erysipelas].
    Author: Ambalov IuM, Kovalenko AP, Usatkin AV, Khomchenko LN.
    Journal: Vrach Delo; 1991 Sep; (9):76-9. PubMed ID: 1759439.
    Abstract:
    The authors determined the content of total immunoglobulins of the E class in the blood plasma: native (IgE) and exhausted by a streptococcal allergen in the dynamics of the disease in 145 patients with erysipelas. The level of antistreptococcal reagins was evaluated. It was established that at the onset of erysipelas the concentration of IgE and a-IgE showed a short-term increase in 52 +/- 4% and 87 +/- 3% of patients correspondingly. During convalescence the level of these antibodies did not differ from that of the normal excluding high risk patients for recurrence. The participation of IgE-mediated type of allergic reactions in the pathogenesis of erysipelas is suggested. It is recommended to use the content of IgE and a-IgE for the prognosis of immediate and remote recurrences of erysipelas.
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