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  • Title: Fluorescent method for evaluation of cholinesterase inhibitors.
    Author: Gainullina ET, Kondratyev KV, Ryzhikov SB, Taranchenko VF.
    Journal: Bull Exp Biol Med; 2006 Dec; 142(6):751-2. PubMed ID: 17603688.
    Abstract:
    The sensitivity of detection of anticholinesterase compounds (e.g. tacrine) by the biochemical method significantly increased when fluorogenic compound N-(4-(7-diethylamino-4-methylcoumarine-3-yl)phenyl)maleimide was used instead of Ellman's reagent. A kinetic fluorescent method for evaluating cholinesterase inhibitors is proposed.
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