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Title: Leuconoxine, kopsinitarine, kopsijasmine, and kopsinone derivatives from Kopsia. Author: Lim SH, Sim KM, Abdullah Z, Hiraku O, Hayashi M, Komiyama K, Kam TS. Journal: J Nat Prod; 2007 Aug; 70(8):1380-3. PubMed ID: 17608533. Abstract: Four new indole alkaloids were obtained from two Kopsia species, 6-oxoleuconoxine (1) from the leaf extract of K. griffithii and kopsinitarine E (2), kopsijasminine (3), and kopsonoline (4) from the stem-bark extract of K. teoi. The structures of these alkaloids were determined using NMR and MS analysis. Kopsijasminine (3) showed moderate activity in reversing multidrug resistance in vincristine-resistant KB cells.[Abstract] [Full Text] [Related] [New Search]