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  • Title: Synthesis of putative chain terminators of mycobacterial arabinan biosynthesis.
    Author: Smellie IA, Bhakta S, Sim E, Fairbanks AJ.
    Journal: Org Biomol Chem; 2007 Jul 21; 5(14):2257-66. PubMed ID: 17609757.
    Abstract:
    The synthesis of a variety of arabinose derivatives that have been modified at C-5 was achieved from d-arabinose. The 5-fluoro and 5-methoxy compounds were converted into the corresponding farnesyl phosphodiesters as putative chain terminators of mycobacterial arabinan biosynthesis. Biological testing of these materials revealed no effective anti-mycobacterial activity.
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