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  • Title: Characterization of muscarine receptors in rabbit ciliary body smooth muscle using propylbenzilylcholine mustard.
    Author: Takayanagi I, Saito K, Koike K, Satoh M.
    Journal: Gen Pharmacol; 1991; 22(5):851-3. PubMed ID: 1761190.
    Abstract:
    1. A piece of rabbit ciliary body was mounted in organ bath and used as a test organ containing muscarine receptors. 2. A concentration response curve of carbachol was completely inhibited by a 50 min treatment of the smooth muscle preparation with propylbenzilylcholine mustard(PrBCM; 10(-6) M). This treatment was reported to block PrBCM-sensitive muscarine receptors in intestinal smooth muscle completely. 3. It is suggested that an existance of only PrBCM-sensitive muscarinic receptors, though there are two subtypes of muscarine receptors; PrBCM-sensitive and -resistant ones in intestinal smooth muscles.
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