These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The relation of peroxisome proliferator activated receptorbeta and Epithelial Ovarian Carcinoma].
    Author: Yang Y, Hou JQ, Ju HW, Yu ZH, Zhao ZW, Yang S, Yang HJ.
    Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2007 Jul; 23(7):630-2. PubMed ID: 17618585.
    Abstract:
    AIM: To explore the possible relationship between expression of PPAR(pevoxisome prodiferator adivated receptor) beta and clinical pathological features of epithelial ovarian carcinoma (EOC). METHODS: PPARbeta expressions in normal ovaries (n=10), ovarian bordline tumors (n=10), and ovarian serous cystadenocarcinomas (n=46) were investigated by immunohistochemistry and RT-PCR. RESULTS: PPARbeta protein was expressed in normal ovaries and ovarian cancer. PPARbeta protein was found in cytoplasm of tumor cell. PPARbeta expression was 20% revealed in normal ovaries, 50% in bordline tumors 89.1% in serous cystadenocarcinomas(P<0.05), significantly higher than that in bordline tumors (P<0.05). PPARbeta expression was positively correlated with tumor stage, histological grade and lymphonode metastasis (P<0.05). CONCLUSION: High expression of PPARbeta may be related with the differentiation and metastasis of epithelial ovarian carcinoma.
    [Abstract] [Full Text] [Related] [New Search]