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  • Title: Novel chloroenyne-modified amino acid derivatives.
    Author: Gredicak M, Kolonić A, Jerić I.
    Journal: Amino Acids; 2008 Jun; 35(1):185-94. PubMed ID: 17619116.
    Abstract:
    Three groups of chloroenyne-modified amino acids were synthesized. Chloroenyne moiety was attached at the N- or C-terminal amino acid (Tyr, Phe, Val, Gly, Lys) position carrying different protecting groups. Prepared derivatives will be used as building blocks in the synthesis of enediyne-peptide conjugates. Furthermore, reactivity of modified amino acids in the peptide bond formation reaction was tested.
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