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  • Title: Septo-optic dysplasia associated with abnormal pubertal development.
    Author: Amatyakul P, Panthasri T, Vutyavanich T.
    Journal: J Med Assoc Thai; 2007 Jun; 90(6):1239-43. PubMed ID: 17624226.
    Abstract:
    Septo-optic dysplasia (SOD) is a congenital anomaly, that is characterized by a triad of optic nerve hypoplasia, structural brain defects, and hypothalamic-pituitary dysfunction. This condition is very rare and it has never been reported in a Thai population. In the present report, the authors described two SOD cases that presented with primary amenorrhea and abnormal pubertal development. Clinical features. Possible etiology of this condition was reviewed
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