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  • Title: Successful treatment of vancomycin-resistant enterococcus ventriculitis in a child.
    Author: da Silva PS, Monteiro Neto H, Sejas LM.
    Journal: Braz J Infect Dis; 2007 Apr; 11(2):297-9. PubMed ID: 17625782.
    Abstract:
    UNLABELLED: Enterococci are an uncommon cause of CNS infection. A 20 month-old boy, diagnosed with hydrocephalus with ventriculoperitoneal shunt and history of lengthy hospitalization and use of wide spectrum antibiotics, was admitted to the pediatric intensive care unit diagnosed with ventriculitis. On the 14th day of empirical antibiotic therapy (vancomycin and meropenem) the child presented fever while the CSF sample culture evidenced vancomycin-resistant Enterococcus faecium. The patient received intravenous linezolid achieving cerebrospinal fluid sterilization. CONCLUSION: Intravenous linezolid appears to be a safe and effective therapy for vancomycin-resistant enterococcus ventriculoperitoneal shunt infection.
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