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  • Title: The mechanical properties of the rabbit carpal tunnel subsynovial connective tissue.
    Author: Yamaguchi T, Osamura N, Zhao C, Zobitz ME, An KN, Amadio PC.
    Journal: J Biomech; 2008 Dec 05; 41(16):3519-22. PubMed ID: 17631885.
    Abstract:
    The rabbit model is commonly used to study carpal tunnel syndrome (CTS). It has been proposed that the subsynovial connective tissue (SSCT) in the carpal tunnel may play a role in the etiology of CTS, but the material properties of the rabbit SSCT are unknown. The purpose of this study was to develop a method to measure the shear properties of the rabbit SSCT. In six rabbit cadaver forepaws, the excursion of the third digit flexor digitorum superficialis (FDS) and load to failure of the SSCT were measured in a custom device. The mean excursion to full flexion in this model was 7.08mm (S.D. 0.77). The mean shearing force at full flexion was 317 mN (S.D. 166). At full flexion percentage of maximum shear force in the SSCT was 54.5% (S.D. 19.4). The mean energy absorbed at full flexion was 0.29mJ (S.D. 0.31). The mean excursion needed to reach 5% of the maximum shear force was 3.04mm (S.D. 0.99). The testing model presented in this study demonstrates structural parameters to evaluate the shear properties of the SSCT in a rabbit model. The data presented could be used for estimating sample sizes in a more comprehensive study of the effect of CTS on the SSCT properties.
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