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  • Title: Does early morning versus late morning draw time influence apparent testosterone concentration in men aged > or =45 years? Data from the Hypogonadism In Males study.
    Author: Guay A, Miller MG, McWhirter CL.
    Journal: Int J Impot Res; 2008; 20(2):162-7. PubMed ID: 17637790.
    Abstract:
    The Hypogonadism In Males study estimated the prevalence of hypogonadism in men aged > or =45 years. A sub-analysis of patients not receiving testosterone (T) therapy was conducted. Blood draw times were 0800-1000 and 1000-1200 hours. Total T (TT) was not influenced by draw time for any age group; however, significantly greater free T (FT) and bioavailable T (BAT) values were observed in the overall population for earlier draw times. Sex hormone-binding globulin (SHBG) values were significantly lower in men aged 45-64 years at the earlier draw time. In men aged > or =75 years, no significant differences in TT, FT, BAT or SHBG were observed on the basis of draw time. Early morning draw time may not be critical for capturing TT concentrations in men > or =45 years; however, when measuring FT or BAT, an early morning draw time may be preferable for men aged <75 years.
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