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Title: Total synthesis of luotonin A and 14-substituted analogues. Author: Mason JJ, Bergman J. Journal: Org Biomol Chem; 2007 Aug 07; 5(15):2486-90. PubMed ID: 17637970. Abstract: A new and concise synthesis of luotonin A was achieved from the previously described compounds ethyl 4-oxo-3,4-dihydroquinazoline-2-carboxylate and 1-(2-nitrophenyl)prop-2-en-1-one. New 14-substituted luotonin A analogues were prepared using 14-chloroluotonin A as the key intermediate.[Abstract] [Full Text] [Related] [New Search]