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  • Title: cDNA and amino acid sequences of bovine tissue factor.
    Author: Takayenoki Y, Muta T, Miyata T, Iwanaga S.
    Journal: Biochem Biophys Res Commun; 1991 Dec 31; 181(3):1145-50. PubMed ID: 1764065.
    Abstract:
    A cDNA encoding bovine tissue factor has been isolated from a lambda gt11 bovine adrenal cDNA library. The cDNA insert was 1877 base pairs with an open reading frame of 876 base pairs that encoded a presequence of 35 amino acids and a mature tissue factor of 257 amino acids. Bovine tissue factor had three potential N-glycosylation sites, four extracellular cysteine residues, a cytoplasmic cysteine residue, and one tripeptide tryptophan-lysine-serine motif. Identities of the amino acid sequences of the mature forms between the bovine tissue factor and each of human, mouse, and rabbit tissue factors were 70.4%, 57.2%, and 74.1%, respectively.
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