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Title: Yersinia pestis CO92 delta yopH is a potent live, attenuated plague vaccine. Author: Bubeck SS, Dube PH. Journal: Clin Vaccine Immunol; 2007 Sep; 14(9):1235-8. PubMed ID: 17652523. Abstract: An in-frame deletion of the yopH gene in Yersinia pestis CO92 attenuates virulence in both bubonic and pneumonic plague models. When it is used as a live, attenuated vaccine, CO92 delta yopH provides a high degree of protection from parental and respiratory challenge with Y. pestis CO92.[Abstract] [Full Text] [Related] [New Search]