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  • Title: Good pregnancy outcome after prenatal exposure to bleomycin, etoposide and cisplatin for ovarian immature teratoma: a case report and literature review.
    Author: Karimi Zarchi M, Behtash N, Modares Gilani M.
    Journal: Arch Gynecol Obstet; 2008 Jan; 277(1):75-8. PubMed ID: 17653741.
    Abstract:
    AIM: The administration of bleomycin plus etoposide and cisplatin during pregnancy is rare. MATERIALS AND METHODS: We describe a case with good pregnancy outcome after exposure to these chemotherapeutic agents at the third trimester of pregnancy. RESULTS AND DISCUSSION: A pregnant woman with stage IIIc immature teratoma underwent surgical staging, and received two cycles of bleomycin, etoposide and cisplatin from the 29th week of pregnancy until delivery. The patient did not have any evidence of recurrence of ovarian cancer for 1.5 years. Her infant did not have any evidence of minor or major malformations, and showed normal neurological development during 1.5 years of follow-up.
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