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  • Title: Effects of chlorhexidine and sodium hypochlorite on the microhardness of root canal dentin.
    Author: Oliveira LD, Carvalho CA, Nunes W, Valera MC, Camargo CH, Jorge AO.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Oct; 104(4):e125-8. PubMed ID: 17656125.
    Abstract:
    OBJECTIVE: The purpose of this study was to evaluate the effects of endodontic irrigants on the microhardness of root canal dentin. STUDY DESIGN: Thirty extracted single-rooted human teeth were used. The crowns were sectioned at the cementoenamel junction. Each root was transversely sectioned into cervical, middle, and apical segments, resulting in 90 specimens. The 3 sections of each root were separately mounted in an individual silicon device with acrylic resin. The specimens were randomly divided into the following 3 groups (n = 30), according to the irrigant solution used: (1) group 1, control (saline solution); (2) group 2, 2% chlorhexidine gluconate solution; and (3) group 3, 1% sodium hypochlorite (NaOCl). After 15 minutes of irrigation, dentin microhardness was measured on each section at 500 microm and 1000 microm from the pulp-dentin interface with a Vickers diamond microhardness tester in Vickers hardness number (VHN). RESULTS: Data obtained were analyzed using analysis of variance and the Tukey test (5%). Specimens irrigated with 2% chlorhexidine (group 2) or 1% NaOCl (group 3) presented lower values of dentin microhardness, with significant difference in relation to the control group (P < .05). CONCLUSION: It could be concluded that chlorhexidine and NaOCl solutions significantly reduced the microhardness of root canal dentin at 500 microm and 1000 microm from the pulp-dentin interface.
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