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  • Title: Clinical and positron emission tomography findings of chorea associated with primary antiphospholipid antibody syndrome.
    Author: Wu SW, Graham B, Gelfand MJ, Gruppo RE, Dinopolous A, Gilbert DL.
    Journal: Mov Disord; 2007 Sep 15; 22(12):1813-5. PubMed ID: 17659641.
    Abstract:
    A fourteen-year-old right-handed male with a history of attention deficit hyperactivity disorder (ADHD) presented with alternating hemichorea. Laboratory findings included elevated anticardiolipin IgG and anti-beta(2)-glycoprotein I IgG, which were consistent with primary antiphospholipid antibody syndrome. Positron emission tomography (PET) imaging revealed altered striatal metabolism in his left putamen while he was exhibiting right-sided hemichorea. His symptoms resolved on prednisone; however, his antiphospholipid antibody profile remained markedly abnormal despite being symptom-free for 26 months.
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