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  • Title: [Correlation between the results of Doppler velocimetry with spectral analysis and the viscosity of cord blood].
    Author: Steel SA, Pearce JM, Nash G, Christopher B, Dormandy J, Bland JM.
    Journal: Rev Fr Gynecol Obstet; 1991 Feb 25; 86(2 Pt 2):168-71. PubMed ID: 1767168.
    Abstract:
    The contribution of rheological factors to be impedance of blood flow in the umbilical artery as determined by continuous wave Doppler ultrasound was investigated. Of the 51 pregnancies recruited, six were complicated by pre-eclampsia, 10 by intrauterine growth retardation, 15 by both pre-eclampsia and fetal growth retardation, and there were 20 controls. A significant correlation was demonstrated between both plasma viscosity and gestational age and the resistance index used to characterize the Doppler waveform. Multiple regression analysis demonstrated that changes in plasma viscosity explained 55 p. cent of the variance seen in the resistance index and that this was statistically significant. This finding is, however, unlikely to be of clinical significance as whole blood viscosity had an insignificant effect on the impedance in the umbilical artery. We postulate that vascular factors such as the number and calibre of the placenta arterioles are a more important determinant of umbilical artery impedance.
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