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  • Title: The targets of CAPRI rounds 6-12.
    Author: Janin J.
    Journal: Proteins; 2007 Dec 01; 69(4):699-703. PubMed ID: 17671980.
    Abstract:
    Six protein-protein complexes and two homodimeric proteins involved in a variety of biological processes were offered as targets to CAPRI by crystallographers in Rounds 6-12. CAPRI predictor groups had to predict their structure by docking the free proteins, which they did with a degree of success that depended largely on the amplitude of the conformation changes. In one case at least, the prediction pointed to alternative possibilities of interactions in the crystal of a complex, showing that docking methods have value even when there is an experimental structure.
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