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  • Title: [Efficiency of a hospital stage of complex treatment in adult patients with pulmonary tuberculosis].
    Author: Aminev KhK, Azamatova MM, Giliazitdinov KA, Fattakhova LZ, Gol'ianova KI, Toptsiĭ VG.
    Journal: Probl Tuberk Bolezn Legk; 2007; (6):4-9. PubMed ID: 17672054.
    Abstract:
    To evaluate the efficiency of an inpatient stage of treatment in adult patients with tuberculosis (n = 4326, including 54.9% with lung decay cavities, 52.5% with bacterial isolation, 44.9% with new-onset tuberculosis), the authors examined the 2004 data of therapeutic department of 12 tuberculosis care facilities in the Republic of Bashkortostan. Drug resistance was established in 23.4%, including multidrug resistance in 13.3% (among those with new-onset tuberculosis, these figures were 13.2 and 4.8%, respectively). By discharge, complex etiopathogenetic treatment using artificial pneumothorax and pneumoperitoneum could cease bacterial isolation in 51.6%, including in 37.1% of those with drug resistance and in 31.8% of those with multiple drug resistance. Among the patients with new-onset tuberculosis, these figures were much higher and equal to 73.3, 66.9, and 60.5%, respectively. Decay cavity closure was achieved in 23.9%, including in 13.5% of those with drug resistance and in 9.5% of those with multiple drug resistance (among the patients with new-onset tuberculosis, these figures were 44.6, 33.3, and 24.3%, respectively). The important factors suppressing the higher efficiency of inpatient treatment are comorbidity and incompliance that reduce bacterial isolation cessation to 16.2 and 21.4%, respectively). In patients with new-onset pulmonary tuberculosis, an average of 156.4 bed-days were required to cease bacterial isolation and 169.7 bed-days were to close decay cavities. To enhance the results of inpatient treatment, it is necessary to perform an effective treatment of comorbidity, to eliminate the factors leading to incompliance, and to apply Law phi3-77 "On Prevention of Prevalence of Tuberculosis in the Russian Federation".
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