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  • Title: [Tuberculin sensitivity in children and adolescents with tuberculosis].
    Author: Gubkina MF, Gazizova IK, Ovsiankina ES, Ershova NG.
    Journal: Probl Tuberk Bolezn Legk; 2007; (6):53-6. PubMed ID: 17672062.
    Abstract:
    The specific features of tuberculin sensitivity were studied in 210 children and adolescents aged 4-17 years who had active pulmonary tuberculosis. There were more common significant and hyperergic tuberculin sensitivities, conversion of tubercular tests, and an increase in tuberculin sensitivity. Timely phthisiological examination of patients with these values of tuberculin sensitivity could promote early detection of local forms of tuberculosis in 71.1% of the patients detected on their visit to a doctor. There was a correlation of the hyperergic tuberculin sensitivity with the phase of incomplete calcification in patients with tuberculosis of the intrathoracic lymph nodes, which may suggest that the macroorganism is hypersensitized in patients with slow reparative processes. There is evidence that the Mantoux test with 2 TE of PPD-L preserves its diagnostic value in patients with clinical and X-ray changes in the differential diagnosis of tuberculosis and nonspecific diseases of the lung.
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