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  • Title: [Synthesis and biological properties of 6-oxa-D-homo-8alpha analogues of steroid estrogens].
    Author: Shavva AG, Morozkina SN, Ishchenko IV, Eliseev II, Selivanov SI, Abusalimov ShN, Selivanov SS, Kameneva IIu, Eshchenko ND.
    Journal: Bioorg Khim; 2007; 33(3):310-4. PubMed ID: 17682386.
    Abstract:
    Modifications of 6-oxa-D-homo-8alpha-analogues of steroid estrogens were found to lead to a complete loss of the uterotropic and hypertriglyceridemic activities. These compounds may be promising for the design on their basis of inhibitors of the steroid hormone metabolism and transporters of other compounds to the estrogen target organs.
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