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  • Title: [Directed introduction of amino groups by internucleotide phosphate group during solid-phase synthesis of oligodeoxyribonucleotides. Preparation of biotinylated oligonucleotide probes].
    Author: Veĭko VP, Ratmanova KI, Osipov AS, Bulenkov MT, Pugachev VV.
    Journal: Bioorg Khim; 1991 May; 17(5):685-9. PubMed ID: 1768294.
    Abstract:
    An efficient procedure for solid-phase synthesis of amino-oligonucleotides has been developed, leading to direct introduction of an aliphatic primary amino group at the internucleotide phosphate. Amino-oligonucleotides were successfully used for preparation of biotinylated oligonucleotides.
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