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  • Title: The control of impurities in amitriptyline hydrochloride using a reversed-phase hybrid stationary phase.
    Author: Dixon SP, Lodi A, Miller JH, Skellern GG.
    Journal: Pharmeur Sci Notes; 2005 Aug; 2005(1):15-20. PubMed ID: 17687889.
    Abstract:
    An isocratic reversed-phase liquid chromatographic method is described using a hybrid column for the control of synthetic impurities potentially found in amitriptyline hydrochloride. The method has been validated and is capable of controlling impurities to 0.1 per cent.
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