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  • Title: Amphetamine-associated ischemic stroke: clinical presentation and proposed pathogenesis.
    Author: De Silva DA, Wong MC, Lee MP, Chen CL, Chang HM.
    Journal: J Stroke Cerebrovasc Dis; 2007; 16(4):185-6. PubMed ID: 17689416.
    Abstract:
    We report a young lady with acute left middle cerebral artery infarction after acute intake of amphetamine. This is the first case report of amphetamine-induced ischemic stroke with serial angiography and transcranial color-coded Doppler studies. The temporal sequence of stenosis of at least 3 weeks with subsequent complete resolution by 3 months and a "beaded" appearance on angiography support vasculitis or vasospasm as the pathogenesis of ischemic stroke in this patient. The presence of microembolic signals supports acute thrombosis at the site of vasculitis/vasospasm with distal embolism.
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