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  • Title: Tetanus-induced acute kidney injury in a renal transplant recipient.
    Author: Lima EQ, Silva RG, Fernandes IM, Abbud-Filho M, Burdmann EA.
    Journal: Am J Trop Med Hyg; 2007 Aug; 77(2):400-2. PubMed ID: 17690422.
    Abstract:
    A 48-year-old renal transplant recipient who developed tetanus 6 years after transplantation is described. His immunosuppressive protocol was mofetil mycophenolate, sirolimus, and prednisone. The patient presented symptoms of severe tetanus with autonomic dysfunction, requiring ICU care and mechanical ventilation. His clinical course was marked by development of tetanus-induced acute kidney injury and sepsis. He was discharged after 37 days of hospitalization with recovered renal function. Tetanus is a preventable disease associated with a high fatality rate. Its treatment is difficult and requires specialized and intensive care. This case highlights the crucial importance of following adequate immunization guidelines in transplant recipients.
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