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  • Title: Biosynthesis of castor oil: effect of polyamines on the acylation of lysophosphatidic acid at the sn-2 position with ricinoleic acid.
    Author: Tomosugi M, Ohshiro A, Hara S, Ichihara K.
    Journal: Biosci Biotechnol Biochem; 2007 Aug; 71(8):2052-6. PubMed ID: 17690446.
    Abstract:
    Polyamines with diamine structures of chain length longer than 3C were essential for the synthesis of phosphatidic acid (PA) from ricinoleoyl-CoA and lysophosphatidic acid (LPA) by the castor LPA acyltransferase reaction, suggesting that polyamines modulate enzyme affinity for the acyl-CoA substrate in vivo.
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