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  • Title: A new ester isolated from Ferula assa-foetida L.
    Author: Abd El-Razek MH.
    Journal: Biosci Biotechnol Biochem; 2007 Sep; 71(9):2300-3. PubMed ID: 17690448.
    Abstract:
    A new caffeic acid cinnamyl ester (1) was isolated from the n-hexane-soluble fraction of an MeOH extract of the gum resin of Ferula assa-foetida L. The structure was determined to be (2E)-3,4-dimethoxycinnamyl-3-(3,4 diacetoxyphenyl) acrylate on the basis of spectroscopic data including 1D- and 2D-NMR. Compound 1 showed moderate activity for inhibiting LPS-induced nitric oxide production in murine macrophage RAW264.7 cells, with an IC50 value of 54.9 microm.
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