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  • Title: A novel antiplasmodial 3',5'-diformylchalcone and other constituents of Friesodielsia obovata.
    Author: Joseph CC, Magadula JJ, Nkunya MH.
    Journal: Nat Prod Res; 2007 Sep; 21(11):1009-15. PubMed ID: 17691050.
    Abstract:
    Phytochemical investigation of the stem and root barks of Friesodielsia obovata Benth (Annonaceae) afforded new 3',5'-diformyl-2',4',6'-trihydroxychalcone and N-formyl-7-hydroxyglaucine together with five known compounds, 3',5'-dimethyl-2',4',6'-trihydroxychalcone, (-)-crotepoxide, demethoxymatteucinol, lawinal, and benzyl benzoate. 3',5'-diformyl-2',4',6'-trihydroxychalcone indicated significant antiplasmodial, cytotoxicity, and larvicidal activities.
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