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  • Title: Increased iron absorption in uroporphyrin-treated rats.
    Author: Weaver GA, Franck CA, Harris MD, Peters T.
    Journal: Digestion; 1991; 49(3):151-5. PubMed ID: 1769430.
    Abstract:
    Rats were given 59Fe (28 micrograms) together with doses of 0, 2 and 200 micrograms of uroporphyrin III in paired observations. Absorption of 59Fe was determined by comparing whole body counts of the rats 30 min and 7 days after dosing. Prior treatment with 200 micrograms of uroporphyrin twice daily for 3 days was associated with significantly increased 59Fe absorption of 6.2% compared to the absorption of 4.6% without uroporphyrin (control) and 4.6% with a 2-micrograms dose (p less than 0.05).
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