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  • Title: [Isolation of factor IX concentrate from cryosupernatant of donor's plasma].
    Author: Fetisova LV, Viazova EP, Khametova RN, Shuvalova AL, Azhigirova MA, Lazarev VA, Zeĭnalov AM.
    Journal: Gematol Transfuziol; 1991 Jun; 36(6):34-6. PubMed ID: 1769497.
    Abstract:
    Soviet anion-exchangers were comparatively studied to specify an optimal carrier useful for isolation of factor ix of the blood coagulation system from donor's blood cryosupernatant. The main criteria of gel selection were the yield and purification degree of factor IX, as well as its specific activity and concentration in eluates. It has been shown that DEAE-agarose 6B-CL, possessing pronounced activity with respect to specific sorption of factor IX, meets these requirements to the greatest degree.
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